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Biotin-PEG3-NHS ester
- 商品名称： Biotin-PEG3-NHS ester
- Product No.： BK03241
- Product Name： Biotin-PEG3-NHS ester
- 中文名称： 生物素-三聚乙二醇-丙烯酸琥珀酰亚胺酯
- Appearance： 液态
- CAS.： 1253286-56-4
- Formula： C23H36N4O9S
- M.W.： 544.62
相关描述
Biotin-PEG3-NHS ester is a biotinylation reagent based on polyethylene glycol (PEG3), consisting of three structural components: Biotin provides high-affinity binding to streptavidin; the PEG3 chain enhances molecular solubility and reduces non-specific adsorption; and the terminal NHS ester reacts specifically with molecules containing primary amines (-NH₂) such as proteins, peptides, or nanomaterials to form stable amide bonds.
The production process typically involves two coupling steps: first, activating the carboxyl group of biotin with NHS to generate Biotin-NHS, which then reacts with amino-functionalized PEG3 in a buffer solution. The target product is obtained after purification.
This reagent is widely used in protein labeling, affinity chromatography purification, cell imaging, and PROTAC molecule development, serving as a key tool for achieving targeted conjugation and functionalization in biomedical research.
所属分类： 生物素链接剂
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