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Benzyl-PEG24-MS
- 商品名称： Benzyl-PEG24-MS
- Product No.： BK03341
- Product Name： Benzyl-PEG24-MS
- 中文名称： 苄基-二十四聚乙二醇-甲磺酸酯
- Appearance： 液态
- CAS.： 2218463-20-6
- Formula： C56H106O27S
- M.W.： 1243.49
相关描述
Benzyl-PEG24-MS (CAS No.: 2218463-20-6) is a PEG-based PROTAC linker with the molecular formula C₅₆H₁₀₆O₂₇S and a molecular weight of 1243.49. Its structure consists of a benzyl-protected terminal, 24 ethylene glycol repeating units, and a methanesulfenyl (MS) functional group, forming a linear flexible chain. It is produced using monodisperse PEG24 synthesis technology, with chain length precisely controlled through methanesulfenylation and hydrolysis reactions. The product is obtained with high purity after purification monitored by TLC. This linker is widely used in PROTAC molecule construction, connecting E3 ubiquitin ligase ligands with target protein ligands to enable selective degradation of target proteins via the ubiquitin-proteasome system, holding significant application value in cancer targeted therapy and signal pathway research.
所属分类： 苄基链接剂
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