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Benzyl-PEG18-THP
- 商品名称： Benzyl-PEG18-THP
- Product No.： BK03177
- Product Name： Benzyl-PEG18-THP
- 中文名称： 苄基-十八聚乙二醇-四氢吡喃醚
- Appearance： 液态
- Formula： C48H88O20
- M.W.： 985.20
相关描述
Benzyl-PEG18-THP is a PEG-based PROTAC linker composed of a benzyl group, 18 ethylene glycol repeating units, and a tetrahydrofuran ether group. It has a large molecular weight and exhibits good water solubility and biocompatibility. The production process employs high-purity chemical synthesis, with precise control over reaction conditions and purification steps to ensure a product purity of ≥98%, verified by quality control methods such as LC/MS and NMR. As a core component of PROTAC technology, it connects the E3 ubiquitin ligase ligand with the target protein ligand, utilizing the ubiquitin-proteasome system to achieve selective degradation of the target protein.
所属分类： 苄基链接剂
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