THP-PEG7-t butyl ester


THP-PEG7-t butyl ester
  • 商品名称: THP-PEG7-t butyl ester
  • Product No.: BK03331
  • Product Name: THP-PEG7-t butyl ester
  • 中文名称: 四氢吡喃醚-七聚乙二醇-丙酸叔丁酯
  • Appearance: 液态
  • Formula: C26H50O11
  • M.W.: 538.67

相关描述

THP-PEG7-t butyl ester is a polyethylene glycol (PEG) derivative containing a tetrahydrofuran ether (THP) protecting group and a t-butyl ester group, with a molecular formula of C₂₃H₄₆O₉ and a molecular weight of approximately 454.6. Its structure consists of a seven-unit polyethylene glycol (PEG7) chain connecting the THP protecting group and the t-butyl ester group. The THP group is used to protect hydroxyl groups, while the t-butyl ester group can be deprotected under acidic conditions to generate a carboxyl group. The production process includes synthesizing a low-molecular-weight PEG chain, introducing disulfide bonds, connecting the t-butyl ester group via esterification, and finally incorporating the THP protecting group. This compound is primarily used in drug synthesis as a protecting group or as a hydrophilic spacer to enhance molecular water solubility, and it is applicable for material surface modification and lipidic assembly research.
 

所属分类: 四氢吡喃醚链接剂


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