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MS-PEG6-MS
- 商品名称： MS-PEG6-MS
- Product No.： BK03358
- Product Name： MS-PEG6-MS
- 中文名称： 甲磺酸酯-六聚乙二醇-甲磺酸酯
- Appearance： 液态
- CAS.： 109789-40-4
- Formula： C14H30O11S2
- M.W.： 438.51
相关描述
MS-PEG6-MS is a PEG-based PROTAC linker. Its structure consists of six repeating ethylene glycol units (PEG6) and methanesulfonate (Ms) functional groups at both ends, with a molecular formula of C₁₄H₃₀O₉S and a molecular weight of approximately 392.46. The production process involves synthesizing the PEG chain through the polymerization of ethylene oxide and ethylene glycol, followed by chemical modification to introduce methanesulfonate groups, ensuring high purity (≥95%) and chemical stability. This product is primarily used in the synthesis of PROTAC molecules, which connect E3 ubiquitin ligase ligands with target protein ligands to enable degradation of target proteins via the ubiquitin-proteasome system. It is widely applied in the fields of tumor-targeted therapy and drug development.
所属分类： 甲磺酸酯链接剂
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