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Carbonic acid, (1α,8α,9α)-bicyclo[6.1.0]non-4-yn-9-ylmethyl (2,5-dioxo-1-pyrrolidinyl) ester, rel-
![Carbonic acid, (1α,8α,9α)-bicyclo[6.1.0]non-4-yn-9-ylmethyl (2,5-dioxo-1-pyrrolidinyl) ester, rel-](/npublic/img/s.png "Carbonic acid, (1α,8α,9α)-bicyclo[6.1.0]non-4-yn-9-ylmethyl (2,5-dioxo-1-pyrrolidinyl) ester, rel-")
- 商品名称： Carbonic acid, (1α,8α,9α)-bicyclo[6.1.0]non-4-yn-9-ylmethyl (2,5-dioxo-1-pyrrolidinyl) ester, rel-
- Product No.： BK03182
- Product Name： Carbonic acid, (1α,8α,9α)-bicyclo[6.1.0]non-4-yn-9-ylmethyl (2,5-dioxo-1-pyrrolidinyl) ester, rel-
- 中文名称： REL-((1R,8S,9R)-双环[6.1.0]壬-4-炔-9-基)甲基 (2,5-二氧代吡咯烷-1-基)碳酸酯
- CAS.： 1493802-77-9
- Formula： C15H17NO5
- M.W.： 291.30
相关描述
Carbonic acid, (1α,8α,9α)-bicyclo[6.1.0]non-4-yn-9-ylmethyl (2,5-dioxo-1-pyrrolidinyl) ester, rel-is a carbonate ester compound containing a bicyclo[6.1.0]non-4-yne skeleton, with a molecular formula of C₁₅H₁₇NO₅ and a molecular weight of 291.3. Its structure consists of a (2,5-dioxopyrrolidin-1-yl) group connected to a (1α,8α,9α)-bicyclo[6.1.0]non-4-yn-9-ylmethyl group via a carbonate ester bond, forming a highly reactive alkyne-NHS ester structure. The production process typically involves an esterification reaction between the bicyclic alkyne alcohol and succinimide carbonate, requiring strict control of reaction conditions to avoid by-products. This compound is widely used in bioorthogonal click chemistry, such as efficiently coupling with azide-labeled biomolecules (e.g., proteins, nucleic acids) through SPAAC reactions, and has important applications in drug development, biological imaging, and materials science.
所属分类： 氧代吡咯烷链接剂
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